AOD-9604

Limited human data

Also known as: hGH fragment 176-191

A fragment of the C-terminal region of human growth hormone historically investigated for fat metabolism without full GH receptor agonism claims.

Fat loss

Mechanism (plain language)

Derived from hGH 176–191 region; researched for lipolytic signaling distinct from intact GH’s broader anabolic profile—mechanistic details remain debated.

What research suggests

Some early human and preclinical work explored fat-loss endpoints. Effect sizes and consistency have not matched modern incretin therapeutics in large modern RCTs.

Uncertainties & risks

Evidence base is older and mixed. Not a substitute for lifestyle or approved obesity therapies. Product authenticity in gray markets is a recurring diligence issue.

STACKD study summaries

Start with our in-house roundups—plain-language synthesis of the research, with primary sources cited at the bottom of each.

STACKD summaryLimited human data
AOD-9604: an old GH-fragment ideaEarly fat-metabolism research that modern therapeutics have outrun.

Primary sources

Secondary citations for verification. Prefer the STACKD summary above for context before opening these.

The effects of the human GH fragment AOD9604 on carbohydrate and lipid metabolism
2000 · human
Early human metabolic exploration of AOD9604.