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CJC-1295

Limited human data

Also known as: CJC-1295 DAC · Modified GRF 1-29

A growth hormone–releasing hormone (GHRH) analogue discussed for GH-axis support. Often mentioned with ipamorelin in fitness forums as a commonly discussed pairing.

Mechanism (plain language)

Stimulates pituitary GH release via GHRH receptor pathways. DAC variants prolong half-life; non-DAC (Mod GRF) versions are shorter-acting—labels online are frequently imprecise.

What research suggests

Some human pharmacokinetic and GH-response data exist for CJC-1295 constructs. Broader physique and recovery claims largely rely on GH physiology rather than large outcome trials in healthy athletes.

Uncertainties & risks

GH elevation carries theoretical risks (edema, insulin resistance, IGF-1 elevation). Compound identity (DAC vs non-DAC) is often unclear in gray-market products. Not a substitute for clinical GH deficiency care.

STACKD study summaries

Start with our in-house roundups—plain-language synthesis of the research, with primary sources cited at the bottom of each.

Primary sources

Secondary citations for verification. Prefer the STACKD summary above for context before opening these.

Often discussed with…

Commonly discussed together

CJC + Ipamorelin

Fitness discussions often group a GHRH analogue (CJC-1295 / Mod GRF) with ipamorelin when talking about GH-axis pulses, sleep, and recovery themes.

Pairing popularity is not evidence of synergy from large RCTs. Confirm peptide identity (e.g., DAC vs non-DAC) in any primary literature you review.

Muscle / GH axis · Sleep / recovery adjunct · Recovery