STACKDSTACKDResearch
Sign up

Compound library

Peptides

Deep profiles for diligence, not product pages. Filter by goal or open any profile for mechanism, evidence, and citations.

45 compounds catalogued

Filter by goal

Showing 11 peptides tagged Muscle / GH axis.

CJC-1295

Limited human data

A growth hormone-releasing hormone (GHRH) analogue discussed for GH-axis support. Often mentioned with ipamorelin in fitness forums as a commonly discussed pairing.

Muscle / GH axis · Recovery · Sleep / recovery adjunct

Ipamorelin

Limited human data

A selective growth hormone secretagogue (ghrelin-receptor agonist) discussed for GH pulses with a relatively favorable selectivity profile in older literature.

Muscle / GH axis · Recovery · Sleep / recovery adjunct

Sermorelin

Limited human data

A 29-amino-acid fragment of growth hormone-releasing hormone (GHRH) that stimulates the pituitary to release the body's own growth hormone. Once an FDA-approved drug for pediatric growth hormone deficiency, it is now mostly used off-label and compounded for adult anti-aging and GH-optimization protocols.

Muscle / GH axis · Longevity / aging

Tesamorelin

Stronger clinical signal

A synthetic GHRH analogue with an approved indication for reducing excess abdominal fat in specific HIV-associated lipodystrophy contexts, often referenced when discussing visceral fat and GH axis research.

Fat loss · Muscle / GH axis · Metabolic

Hexarelin

Limited human data

A synthetic hexapeptide growth hormone secretagogue that activates the ghrelin receptor, producing one of the strongest GH releases of any peptide in its class. Distinct among GH secretagogues for a separate, GH-independent cardioprotective effect documented in animal models.

Muscle / GH axis · Recovery

GHRP-2

Limited human data

A synthetic hexapeptide ghrelin receptor agonist that stimulates growth hormone release. Notable for being the one compound in this family with a real regulatory approval, marketed in Japan as a diagnostic agent for GH deficiency under the name pralmorelin.

Muscle / GH axis · Recovery

GHRP-6

Limited human data

The original growth hormone-releasing hexapeptide, discovered in 1984 and the founding compound of the entire GHRP family, including GHRP-2 and hexarelin. Known for producing the strongest appetite stimulation of the group alongside its GH-releasing effect.

Muscle / GH axis · Recovery

IGF-1 LR3

Emerging

An engineered analog of insulin-like growth factor 1 with reduced binding to its natural binding proteins, giving it a longer half-life and greater potency than native IGF-1. Studied in animals as a research tool for IGF-1 receptor biology, not developed or tested as a human therapeutic.

Muscle / GH axis

A naturally occurring protein that neutralizes myostatin and related growth-inhibiting signals, allowing muscle to grow beyond its normal ceiling. The systemically circulating isoform used in early-phase gene therapy trials for muscular dystrophy, now also sold as a standalone research peptide with no human data in that injectable form.

Muscle / GH axis · Recovery

A splice variant of IGF-1 that muscle tissue produces locally in response to mechanical stretch, stimulation, or injury. Studied mainly in animal and cell models of muscle repair and regeneration; sold as a synthetic research peptide despite very limited direct human data.

Muscle / GH axis · Recovery

PEG-MGF

Emerging

A polyethylene glycol-modified version of MGF designed to extend the parent peptide's minutes-long half-life to several days. A research-chemical product built on real underlying biology, but with essentially no dedicated studies of its own, pegylated form.

Muscle / GH axis · Recovery

Evidence labels

  • EmergingMostly preclinical or early signals; human athletic data is thin.
  • Limited human dataSome human pharmacology or small studies; outcomes for fitness use remain limited.
  • Stronger clinical signalSupported by larger clinical trials in defined medical populations.

Anodized by evidence strength: blue = stronger clinical/human data, violet = limited human data or mechanism, steel = emerging/anecdotal, and amber = an in-house STACKD summary.